Wednesday, November 16, 2011

TED: Open-source for the better-solution


     I don't know exactly when, but I started to have an exceptional fervor towards the study of medicine and human biology. Especially when I was in middle school, I was somehow crazy about the idea of becoming a medical scientist, fighting against detrimental diseases and even working for the WHO, the World Health Organization. Now, I have become more dispssionate about it, after learning that if I take the M.D.-Ph.D. integrated program after four years of undergraduate, 38 will be my age when I could take my first step as a professional. Though, I am still interested in this field for it is directly connected to life and death. And though it might sound rather absurd, I stand for philantrophy and I want to be person society needs.
     In this TED video, Jay Bradner, a researcher at Harvard Medical School, explains a discovery that is so terrific in two ways. His team developed a highly complicated molecule named JQ1, which is a cure for a rare type of midline carcinoma. This cancer is caused by a virulent protein molecule named BRD4. Aside the complex chemical names, this discovery is worth being extoled since it directly helps millions of patients around the globe. Moreover, BRD4 was one of those that were previosly known to be "incurable" or "undrugable." For Dr. Bradner and his team, it is also very special since it gave hope to them that they can find novel cures from studying the basic chemical identities of illness.
     However, the development of JQ1 has another important meaning. Dr. Bradner, along with his scientific experiments on drugs, conducted a social experiment. He implemented a revolutionary and tentative policy, which is to disclose the precious chemical information of their cure. Other researchers, mostly from pharmaceutical companies, would have certainly thought that Dr. Bradner was mad.  Similar to the firms that are infamous to be reticent and to repudiate exchanging information, he could have just kept the information to himself, produce medicine or sell it at an astronomical price. In the pharmaceutical market, chemical information equals fortune. However, Dr. Bradner decided to sacrifice the outcome of his team's diligent work for the sake of the whole society.
     It would have been banal and both sad if the pharmaceutical companies simply benefited from the disclosure of JQ1. This social experiment, as Dr. Bradner says, has been "unfortunately successful," for it was provoactive enough to instigate the number of researchers to augment and more labs to engage in the study of this molecule, enhancing the quality and stability through additional experiments conducted by these newcomers. Bradner's policy expedited the discoveries of new medications and more possible uses of JQ1, as it was found to be effective for Leukemia, multiple myeloma and apidocyte, all thought to be incurable. He expects this cycle of discovery to be incessant. All he did was "opening" the source of his new yet austere form of  cure, and what he recieved was the great euphony of numerous researchers, united under the same perspective of developing new medication. Dr. Bradner's choice was truly laudable, and inspriational.
     I hope the acheivements of Dr.Bradner have successfully derided the selfish pharmaceutical companies. They probably thought he was squandering his oppurtunity, being foolish. Of course, according to their sens of "success," Dr. Bradner is a complete failure. But that "succuss" is too superficial to be recognized as meaningful. One reseracher and his team brought the new spirit into the field of medicine. And for once more, I hope that labs all around the world will come out from their moral depravity and show deference towards Dr. Bradner.

4 comments:

  1. Errr... this was just all what I could do before comming back from Guam...

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  2. Decoy post made before going to Guam haha you should have posted nothing at all Minwoo ㅋㅋ

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  3. Blue comic is right! But no worries about the Decoy Post. I'm not too worried about deadlines as long as my students aren't playing Tetris when they should be doing something. Guam is a perfect excuse. But you could have been doing this instead of playing on the beach.

    Good stuff - and you actually forgot to underline a few SAT words. They all work, and there are only a few places where it sounds a little bit thesaurusy. I'm glad students learn things while watching these videos, especially if it is related to their personal interests. I'm very happy with the quality of this assignment for almost every student. Too bad about the length of time it takes to become a doctor...but open heart surgery is not like baking a cake.;)

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